Molecular & Cellular Biotherapies

Molecular & Cellular Biotherapies (MCB)

The MCB track concerns two major categories of biotherapeutics applications: cell and gene therapy, and biopharmaceuticals. Cell and gene therapy differs from drug therapy in that it concerns the use of ‘custom or « à la carte » therapeutic agents created for a individual patients, a domain in which few manufacturers operate. Biopharmaceuticals are complex macromolecules created by biotechnology, and involve genetic manipulation of living organisms, which differ from conventional chemically synthesized small molecules.

The specific pharmacological and immunological features of biotherapy products, considered to constitute a new generation of drugs, are studied in conjunction with the characteristics of target populations, clinical follow-up, and biological monitoring.
The aim of this track is to train students of advanced scientific level in the field of biotherapy in order to prepare for careers in academia. These students may also find opportunities in industry at the national, European, and international level, particularly in biotechnology and medical research laboratories in teaching hospitals) , as well as in cell and gene therapy firms.

The MCB program is divided into several course units. The first one covers the background and fundamental biological concepts needed to understand the various biotherapeutic approaches. It also provides an introduction to biological considerations involved in the use of therapeutic tools. The second unit addresses each biological system individually. The remaining two units deal with the study of specific examples, industrial aspects, and regulatory issues involved in the use of various types of biotherapeutic tools, as well as to clinical applications.

Semester 3

Mandatory courses

Open Your Mind Seminars
Interdisciplinary week (3 ECTS)
Transversal skills development (3 ECTS)
Gene Transfer Strategies (4 ECTS)
Basic Immunology in Biotherapies (4 ECTS)
Stem cells and disease modelling (3 ECTS)
Gene and cell therapy: Clinical applications Part.1 (3 ECTS)
Gene and cell therapy: Clinical applications Part.2 (3 ECTS)
Cancer Therapies (4 ECTS)

3 ECTS to be picked among

Tissue Engineering: Clinical Applications
Principles in tissue engineering

One course of 3 ECTS in another Master (subject to Master chairs’ authorizations)

Semester 4

Mandatory courses

Ethical and Industrial Aspects (3 ECTS)
Research Internship (27 ECTS)

As far as the non mandatory courses are concerned, the students’ choices will have to be discussed with the track chairs and will be finalized during the interdisciplinary week, taking the student’s personal background and interests into consideration. It will then be validated in a co-signed contract of study.

The courses students will eventually attend will also depend on actual availability: some courses might not open because of an insufficient number of attendees, while others may have a limited capacity and not be able to offer a seat to all.

As indicated, a course may be offered to BME Paris students outside the track which supports it. In such cases, priority will be given to students enrolled in the supporting track.

Students enrolled in other ENSAM, Université Paris Descartes or Université PSL programs may also attend a BME Paris course, provided that:

  • their respective program chairs support their application
  • the course is not already full
  • the relevant BME Paris chairs accept their applications which must include a CV and a motivation letter