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Bioengineering and Innovation in Neurosciences (BIN)

A. Klarsfeld P-P. Vidal
ESPCI ParisTech
Université Paris Descartes
The Bioengineering and Innovation in Neurosciences (BIN) training program, like the other specialties of the BME-Paris Master program, leaves a wide part to interdisciplinarity. It is designed both for engineering school students, and for university students having a robust initial training in basic sciences or medicine. Courses will mesh engineering, mathematics, and computer concepts with molecular, cellular and systems neuroscience. This speciality is hosted by ESPCI ParisTech, ENSAM ParisTech and Paris Descartes.

Our ambition is that through courses, seminars, social events, conferences and collaborative interactions, BIN students will contribute to bridge the gap between basic, clinical, and engineering neuroscience. We believe it is a key issue for both industry and medicine in the 21st century, because of :

  1. aging of the world population, which will considerably increase the prevalence of neurodegenerative diseases, and more generally of sensory and motor handicaps. These will require the development of new biomedical devices and molecular tools to better (i) diagnose neurological diseases, (ii) evaluate their progression or treatment, and (iii) remediate disease- or age-associated handicaps, to which doctors will be confronted increasingly often.
  2. strong demands from a broadening range of industries, way beyond the biomedical ones, including aviation, automobile, sports, and videogames. There is indeed an increasing need to understand how humans interact with their environments in general and with the new complex working environments of today in particular (human factor). Many industries will thus require engineers with both good engineering skills and basic knowledge of neurophysiology.
  3. the requirement of integrative methods and concepts, from the behavioral to the molecular level, to understand how the central nervous system functions, and can be repaired and enhanced. The neurosciences thus cover almost all biomedical technologies and applications. They illustrate well the interdisciplinarity that lies at the heart of biomedical engineering, because they strongly require the collaboration of doctors and engineers, combining many different skills, in optics, electronics, informatics, robotics, physiology, ergonomy, chemistry...
The BIN specialty has also an industrial orientation, by :
  1. relying on many lecturers from research and development (R&D) departments of major companies, as well as start-ups. Technical and industrial aspects will be emphasized, but also the eventual entrepreneurial efforts (successful or not) involved.
  2. offering a practical initiation to innovative entrepreneurship through a Business plan workshop.
  3. encouraging students to apply for their 2nd semester internship in an industrial R&D laboratory or a hospital department.
Courses : an introductory teaching unit will mainly provide a comprehensive overview of the structure and function of the nervous system, as well as basic notions of statistics for biology. The focus will be both on systems and cellular neuroscience, providing the biological notions required for engineering students to follow the BIN track, while refreshing and/or complementing knowledge previously acquired by science and medical students.

Other courses will cover human-machine, brain-machine and brain-computer interfaces (from principles and design to practical implementation and a wide array of "neuroengineering" applications), the imaging and manipulation of neuronal and brain activity, predictive chemistry for neuroscience (from design to clinical testing), microfluidics and other innovative miniaturized biotechnologies for the nervous system, statistics, computer modeling of neuronal networks and their applications... (more detailed presentations of several teaching units can be uploaded via the links below).

Employment opportunities : the interdisciplinary training and experience acquired through the BIN specialty provide employment opportunities in numerous professional fields, such as the medical device industry (for medical bioimaging, or advanced sensory and motor remediation), or the pharmaceutical, cosmetics and chemical industries (drug design, biosensors), as well as robotics, or the defense, the sport, the automobile and the videogame industries. The BIN specialty can also lead to a PhD thesis in an academic or industrial research laboratory, and subsequently to an academic career in the medical or scientific fields.



Semester 3 (two subtracks may be offered) Semester 4
UE 3.0 Seminars & conferences (common to all specialties) UE 4.0 Ethical aspects of bioengineering
UE 3.1

lnterdisciplinary week (common to all specialties)

UE 4.1
UE 3.2 Tutored project and methodologies (common to all specialties) UE 4.2 Research internship
UE 3.3 Refresher courses  
UE 3.4
UE 3.5 Miniaturisation for neuroscience
UE 3.6 Drug design for neurological diseases
UE3.7-8 Brain-computer interfaces: from modeling to engineering
UE 3.9
UE 3.10
UE 3.11
UE 3.12 Movement analysis and locomotion (common with BM²)


Arts et Métiers ParisTech
Université Paris Descartes
Master BME Paris