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BME Seminars - Raphaël Voituriez


Seminar announcement flyer

We are pleased to announce that this Friday, November 23 2018, we will have the great pleasure of hosting a talk given by Raphaël Voituriez, Director of Research at the CNRS, Laboratoire de Physique Théorique de la Matière Condensée and Laboratoire Jean Perrin. The conference will be held  between 1.30 pm and 3 pm in lecture theatre Bezier at ENSAM ParisTech. The seminar topic will be “Physics of cell migration: from cell mechanics to trajectories and exploration”.

Cell movement is involved in many biological processes such as development, wound healing, immunity or cancer metastasis, and is characterized by very diverse migration modes. Recent studies show that cells can adapt to environmental cues, such as adhesion and geometric confinement, thereby readily switching their mode of migration. Among this diversity of motile behaviors,  flows of the cellular "material" -- the actin cytoskeleton -- have emerged as a highly conserved feature. Based on physical models of cytoskeleton dynamics, I will argue that the various observed migration modes are continuous variations of elementary locomotion mechanisms, which rely on a very robust physical property of the cell cytoskeleton : its ability to sustain flows at the cell scale. This central role of cytoskeleton flows will be shown to affect the large scale properties of cell trajectories.


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Université Paris Descartes
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